Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.40 |
| ▸ | ARG2 | P78540 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7441473 | 0.87 | ARG1 (0.41) | ARG1ARG2GABRA5GABRB2GABRA1 | |
| SCHEMBL26127861 | 0.86 | GNAO1 (0.44) | ARG1ARG2GNAI3GNAO1GNAI1 | |
| SCHEMBL3147437 | 0.83 | SSTR4 (0.36) | EPHX1CCR2CYP2D6 | |
| SCHEMBL4969315 | 0.81 | ARG1 (0.41) | ARG1ARG2GABRA5GABRB2GABRA1 | |
| SCHEMBL1724160 | 0.78 | ITGB3 (0.43) | ARG1ARG2TSHRPMP22GNAI3 | |
| SCHEMBL20683515 | 0.78 | ARG1 (0.38) | ARG1ARG2GABRA5GABRB2GABRA1 | |
| SCHEMBL31340040 | 0.76 | SLC6A1 (0.39) | ARG1ARG2GABRA5GABRB2GABRA1 | |
| SCHEMBL8873859 | 0.74 | GABRA5 (0.44) | ARG1ARG2GABRA5GABRB2GABRA1 | |
| SCHEMBL15910211 | 0.74 | GABRA5 (0.44) | ARG1ARG2GABRA5GABRB2GABRA1 | |
| SCHEMBL3271255 | 0.73 | CYP1A2 (0.39) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679413-B | New 3-([1,2,4]triazolo[4,3-a]pyridin-7-yl)benzamide derivatives | ALMIRALL LAB | 2013-07-03 | — | — | CN | disclosed |
| CN-102639132-A | Novel 7-phenyl- [1,2,4] triazolo [4,3-a ] pyridin-3 (2H) -one derivatives | ALMIRALL SA | 2012-08-15 | — | — | CN | disclosed |
| CN-102026972-A | New substituted spiro[cycloalkyl-1,3'-indol]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors | ALMIRALL SA | 2011-04-20 | — | — | CN | disclosed |
| CN-102015680-A | New substituted indolin-2-one derivatives and their use as p38 mitogen-activated kinase inhibitors | ALMIRALL SA | 2011-04-13 | — | — | CN | disclosed |
| CN-101679413-A | New 3-([1,2,4]triazolo[4,3-a]pyridin-7-yl)benzamide derivatives | ALMIRALL LAB | 2010-03-24 | — | — | CN | disclosed |
| CN-101679417-A | New 4,8-diphenyl-polyazanaphthalene derivatives | ALMIRALL LAB | 2010-03-24 | — | — | CN | disclosed |