Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.65 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP7 | P09237 | 2/20 | 0.46 |
| ▸ | MMP14 | P50281 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12925480 | 0.78 | HSD11B1 (1.00) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL7428853 | 0.77 | HSD11B1 (0.55) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL9136704 | 0.76 | HSD11B1 (0.53) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL7321453 | 0.75 | POLB (0.66) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL7428842 | 0.75 | HSD11B1 (0.54) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL27584144 | 0.74 | HSD11B1 (0.55) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL180713 | 0.74 | PSIP1 (1.00) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL6129032 | 0.74 | HSD11B1 (0.60) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL3651298 | 0.74 | HSD11B1 (0.66) | HSD11B1PSIP1POLBALDH1A1TP53 | |
| SCHEMBL6428538 | 0.73 | MMP2 (0.57) | HSD11B1PSIP1POLBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553481-A | Substituted sulfonamide derivatives | GRUENENTHAL GMBH (DE) | 2009-10-07 | — | — | CN | disclosed |