Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351418 | 0.96 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL27761078 | 0.85 | EPHX2 (0.51) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4348481 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL4351157 | 0.81 | EPHX2 (0.56) | HTTKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL4351932 | 0.81 | KDM4E (0.41) | LMNAHTTKMT2AMEN1MAPT | |
| SCHEMBL4350105 | 0.81 | MAPT (0.55) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL6227601 | 0.81 | EPHX1 (0.44) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL27761077 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL4354075 | 0.79 | IDO1 (0.46) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL4342192 | 0.78 | MAPT (0.53) | SMN1; SMN2LMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100546977-C | Suppress the new compound and the application thereof of rotamase | JERINI AG (DE) | 2009-10-07 | — | — | CN | claimed |