Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351418 | 0.84 | SMN1; SMN2 (0.48) | HTTALDH1A1EPHX2SMN1; SMN2GAA | |
| SCHEMBL27782816 | 0.81 | SMN1; SMN2 (0.52) | HTTALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL4351157 | 0.80 | EPHX2 (0.56) | EPHX1HTTALDH1A1EPHX2KMT2A | |
| SCHEMBL4341765 | 0.79 | KMT2A (0.54) | EPHX1HTTEPHX2SMN1; SMN2GAA | |
| SCHEMBL4346126 | 0.79 | LMNA (0.61) | HTTALDH1A1EPHX2SMN1; SMN2GAA | |
| SCHEMBL27761078 | 0.77 | EPHX2 (0.51) | EPHX1HTTALDH1A1EPHX2KMT2A | |
| SCHEMBL4354098 | 0.77 | ALDH1A1 (0.47) | HTTALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL27782801 | 0.76 | LMNA (0.67) | HTTALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL4350105 | 0.75 | MAPT (0.55) | HTTALDH1A1SMN1; SMN2GAAHPGD | |
| SCHEMBL6672908 | 0.75 | EPHX2 (0.52) | EPHX1HTTALDH1A1EPHX2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |