Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10937850 | 0.91 | CA5A (0.43) | CA5ACA5BTSHRLMNACYP3A4 | |
| SCHEMBL28163184 | 0.85 | LMNA (0.36) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| SCHEMBL6046913 | 0.78 | TSHR (0.32) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Piperazine SCHEMBL27671947 | 0.78 | LMNA (0.46) | CA5ACA5BTSHRLMNACYP3A4 | |
| Piperazine SCHEMBL27330293 | 0.78 | LMNA (0.46) | CA5ACA5BTSHRLMNACYP3A4 | |
| Piperazine SCHEMBL28185168 | 0.78 | TSHR (0.46) | CA5ACA5BTSHRLMNACYP3A4 | |
| Piperazine SCHEMBL2445779 | 0.77 | TSHR (0.50) | CA5ACA5BTSHRLMNACYP3A4 | |
| Sulfuric Acid SCHEMBL6099988 | 0.77 | TSHR (0.50) | CA5ACA5BTSHRLMNACYP3A4 | |
| Sulfuric Acid SCHEMBL8291975 | 0.77 | TSHR (0.50) | CA5ACA5BTSHRLMNACYP3A4 | |
| Sulfuric Acid SCHEMBL8300104 | 0.77 | TSHR (0.50) | CA5ACA5BTSHRLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103898515-A | Corrosion inhibitor for gas field and preparation method thereof | CHINA NAT PETROLEUM CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-101775338-B | Stable and biodegradable softening agent material, preparation method thereof and softening agent product | EVONIK DEGUSSA SPECIAL CHEMICAL SHANGHAI CO LTD | 2013-07-10 | — | — | CN | disclosed |
| CN-102586039-B | Clothes washing rinsing synergist containing methyl sulfate-based quaternary ammonium salt | JINGZHOU HUOLI 28 SHASHI DAILY CHEMICAL CO LTD | 2013-02-13 | — | — | CN | disclosed |
| CN-102586039-A | Clothes washing rinsing synergist containing methyl sulfate-based quaternary ammonium salt | JINGZHOU HUOLI 28 SHASHI DAILY CHEMICAL CO LTD | 2012-07-18 | — | — | CN | disclosed |
| CN-101775338-A | Stable and biodegradable softening agent material, preparation method thereof and softening agent product | EVONIK DEGUSSA CHINA CO LTD | 2010-07-14 | — | — | CN | disclosed |