Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL27656709 | 0.89 | TSHR (0.40) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Piperazine SCHEMBL27727092 | 0.86 | TSHR (0.39) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| SCHEMBL28163184 | 0.80 | LMNA (0.36) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Sulfuric Acid SCHEMBL10937850 | 0.80 | CA5A (0.43) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Pyrrolidine SCHEMBL3839669 | 0.79 | ALDH1A1 (0.40) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Sulfuric Acid SCHEMBL27784261 | 0.78 | CA5A (0.35) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Piperidine SCHEMBL28253499 | 0.77 | ALDH1A1 (0.45) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| Piperidine SCHEMBL30496139 | 0.77 | ALDH1A1 (0.45) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| SCHEMBL5991 | 0.76 | — | — | |
| SCHEMBL27259142 | 0.76 | TSHR (0.50) | TSHRCYP3A4CA2USP2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100343376-C | MDEA quats with high monoester content in blends with TEA ester quats | DEGUSSA (DE) | 2007-10-17 | — | — | CN | claimed |
| CN-100430462-C | Detergent compositions comprising a cellulose polymer | PROCTER & GAMBLE (US) | 2008-11-05 | — | — | CN | disclosed |
| CN-100343376-C | MDEA quats with high monoester content in blends with TEA ester quats | DEGUSSA (DE) | 2007-10-17 | — | — | CN | disclosed |
| EP-1711458-A1 | METHOD FOR PRODUCING GUANIDINIUM SALTS | MERCK PATENT GmbH (DE) | 2006-10-18 | — | — | EP | disclosed |
| CN-1806035-A | Mdea ester quats with high content of monoester in blends with TEA ester quats | DEGUSSA (DE) | 2006-07-19 | — | — | CN | disclosed |
| CN-1689693-A | Encapsulated materials | INT FLAVORS & FRAGRANCES INC (US) | 2005-11-02 | — | — | CN | disclosed |
| WO-2005075413-A1 | METHOD FOR PRODUCING GUANIDINIUM SALTS | MERCK PATENT GMBH (DE) | 2005-08-18 | — | — | WO | disclosed |
| CN-1531587-A | Detergent compositions comprising cyclodextrin glucanotrasferase enzyme | — | 2004-09-22 | — | — | CN | disclosed |
| CN-1469919-A | Laundry detergent compositions comprising mannosan enzyme and proteinase | ������-�ʲ�����˾ | 2004-01-21 | — | — | CN | disclosed |
| CN-1454252-A | Detergent compositions comprising a maltogenic alpha-amylase enzyme | PROCTER & GAMBLE (US) | 2003-11-05 | — | — | CN | disclosed |
| CN-1219952-A | Use of fabric softener composition | PROCTER & GAMBLE (US) | 1999-06-16 | — | — | CN | disclosed |
| CN-1216575-A | Cleaning compositions comprising endo-dextranase | PROCTER & GAMBLE (US) | 1999-05-12 | — | — | CN | disclosed |
| CN-1192761-A | Printable swelling paste and its use in cable insulation and non-woven fabric prodn. | STOCKHAUSEN CHEM FAB GMBH (DE) | 1998-09-09 | — | — | CN | disclosed |
| CN-1192776-A | Betaine esters capable of liberating alcohols | PROCTER & GAMBLE (US) | 1998-09-09 | — | — | CN | disclosed |
| CN-1153527-A | Perfumes for laundry and cleaning composition | PROCTER & GAMBLE (US) | 1997-07-02 | — | — | CN | disclosed |
| CN-1134169-A | Cellulase fabric conditioning compositions | PROCTER & GAMBLE (US) | 1996-10-23 | — | — | CN | disclosed |
| CN-1101071-A | Fabric care compositions | PROCTER & GAMBLE (US) | 1995-04-05 | — | — | CN | disclosed |
| CN-1026794-C | Perfume particles for use in washing and conditioning compositions | PROCTER & GAMBLE (US) | 1994-11-30 | — | — | CN | disclosed |
| CN-1066680-A | NONIONIC SOIL RELEASE AGENTS | PROCTER & GAMBLE (US) | 1992-12-02 | — | — | CN | disclosed |
| CN-1047336-A | Perfume particles for use in washing and conditioning compositions | PROCTER & GAMBLE (US) | 1990-11-28 | — | — | CN | disclosed |