Cyanide

Cyanide

SCHEMBL27784384

C#N.CCOc1cccc(S(N)(=O)=O)c1N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.50
CA2 P00918 6/20 0.50
CA12 O43570 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 2/20 0.48
PTGES2 Q9H7Z7 1/20 0.45
ALDH1A1 P00352 3/20 0.43
CA7 P43166 3/20 0.40
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA4 P22748 2/20 0.38
CYP2C9 P11712 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
ADRB2 P07550 1/20 0.37
ADRB1 P08588 1/20 0.37
HTR1A P08908 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyanide SCHEMBL27784346 0.82 CA2 (0.47) CA1CA2CA12CA9CA14
SCHEMBL15465584 0.81 HSD17B10 (0.52) CA1CA2CA12CA9CA14
SCHEMBL29469832 0.80 CA1 (0.60) CA1CA2CA12CA9CA14
SCHEMBL5579618 0.80 CA1 (0.60) CA1CA2CA12CA9CA14
SCHEMBL28115347 0.79 CA12 (0.54) CA1CA2CA12CA9CA14
SCHEMBL31411936 0.79 CA1 (0.54) CA1CA2CA12CA9CA14
Fluoride SCHEMBL28042437 0.78 CA1 (0.58) CA1CA2CA12CA9CA14
SCHEMBL30953901 0.78 CA1 (0.52) CA1CA2CA12CA9CA14
Cyanide SCHEMBL27784526 0.77 CA2 (0.42) CA1CA2CA12CA9CA14
SCHEMBL1523031 0.76 CA2 (0.50) CA1CA2CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101779124-A modulation of chemosensory receptors and ligands associated therewith SENOMYX INC 2010-07-14 CN disclosed