Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.47 |
| ▸ | CA1 | P00915 | 8/20 | 0.47 |
| ▸ | CA9 | Q16790 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1523031 | 0.95 | CA2 (0.50) | CA2CA1CA9CA12PKM | |
| Cyanide SCHEMBL27784384 | 0.82 | CA1 (0.50) | CA2CA1CA9CA12PTGES2 | |
| SCHEMBL31071497 | 0.80 | HTR6 (0.46) | CA2CA1CA9CA12PKM | |
| SCHEMBL1607289 | 0.79 | TTR (0.46) | CA2CA1CA9CA12HTR6 | |
| SCHEMBL529620 | 0.77 | HTR6 (0.60) | CA2CA1CA9CA12PKM | |
| SCHEMBL29581383 | 0.77 | HTR6 (0.60) | CA2CA1CA9CA12PKM | |
| SCHEMBL11153056 | 0.77 | CA2 (0.50) | CA2CA1CA9CA12PKM | |
| SCHEMBL791503 | 0.77 | CA2 (0.50) | CA2CA1CA9CA12PKM | |
| Cyanide SCHEMBL27784410 | 0.76 | ALDH1A1 (0.47) | CA2CA1CA9CA12PKM | |
| SCHEMBL30832693 | 0.76 | GLA (0.44) | CA2CA1HTR6ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101779124-A | modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC | 2010-07-14 | — | — | CN | disclosed |