Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA1 | P00915 | 8/20 | 0.50 |
| ▸ | CA9 | Q16790 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyanide SCHEMBL27784346 | 0.95 | CA2 (0.47) | CA2CA1CA9CA12PKM | |
| SCHEMBL31071497 | 0.85 | HTR6 (0.46) | CA2CA1CA9CA12PKM | |
| SCHEMBL1607289 | 0.83 | TTR (0.46) | CA2CA1CA9CA12HTR6 | |
| SCHEMBL529620 | 0.82 | HTR6 (0.60) | CA2CA1CA9CA12PKM | |
| SCHEMBL29581383 | 0.82 | HTR6 (0.60) | CA2CA1CA9CA12PKM | |
| SCHEMBL791503 | 0.81 | CA2 (0.50) | CA2CA1CA9CA12PKM | |
| SCHEMBL11153056 | 0.81 | CA2 (0.50) | CA2CA1CA9CA12PKM | |
| SCHEMBL30832693 | 0.80 | GLA (0.44) | CA2CA1HTR6ACHEALDH1A1 | |
| SCHEMBL23084437 | 0.80 | ALDH1A1 (0.45) | CA2CA1CA9CA12EP300 | |
| Hydrochloric Acid SCHEMBL4910433 | 0.80 | HTR6 (0.58) | CA2CA1CA9CA12PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361913-A1 | Anti-infective agents | Abbott Laboratories (US) | 2011-08-31 | — | — | EP | disclosed |
| US-7902203-B2 | Anti-infective agents | ABBOTT LABORATORIES, INC. (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1560827-B1 | ANTI-INFECTIVE AGENTS | ABBOTT LAB (US) | 2010-12-29 | — | — | EP | disclosed |
| EP-1401443-A4 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORP (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| US-20050075331-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2005-04-07 | — | — | US | disclosed |
| US-20040167123-A1 | Anti-infective agents | ABBVIE INC. | 2004-08-26 | — | — | US | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
| EP-1401443-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6635635-B2 | 5,5-dioxo-2,3,3a,4-tetrahydro-1 H-pyrrolo(2,1-c)(1,2,4)-benzothiadiazin-7-ol, for example; nervous system disorders; alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) modulators | LES LABORATOIRES SERVIER (FR) | 2003-10-21 | — | — | US | disclosed |
| WO-2002098424-A1 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-12-12 | — | — | WO | disclosed |
| US-20020037894-A1 | Benzothiadiazine compounds | ADIR ET COMPAGNIE (FR) | 2002-03-28 | — | — | US | disclosed |
| EP-1176148-A1 | Benzothiadiazine derivatives, processes for their preparation and pharmaceutical compositions containing them | LES LABORATOIRES SERVIER (FR) | 2002-01-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | CA2 4750/4885CA1 4881/4885CA9 4375/4885 |
| US-20040162285-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CA2 4395/4885CA1 4367/4885CA9 3535/4885 |
| US-20040167123-A1 | Anti-infective agents | SERPINB1, CYP51A1, ZC3HAV1 | CA2 4484/4885CA1 4607/4885CA9 4098/4885 |
| US-20020037894-A1 | Benzothiadiazine compounds | HCAR1, GLRA1, HCAR2 | CA2 1488/4885CA1 1650/4885CA9 4232/4885 |
| US-20050075331-A1 | Anti-infective agents | RPL35, POLI, POLRMT | CA2 4440/4885CA1 4765/4885CA9 4070/4885 |
| US-20040087577-A1 | Anti-infective agents | POLR1C, RPL5, POLB | CA2 4395/4885CA1 4367/4885CA9 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.