Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27785948 | 0.97 | GABRG2 (0.34) | GABRG2GABRB3GABRA2PIK3CANPY1R | |
| SCHEMBL27807929 | 0.97 | PIK3CA (0.34) | GABRG2GABRB3GABRA2PIK3CANPY1R | |
| SCHEMBL27785942 | 0.86 | GABRG2 (0.42) | GABRG2GABRB3GABRA2NPY1RNPY5R | |
| SCHEMBL27807957 | 0.86 | GABRG2 (0.36) | GABRG2GABRB3GABRA2PIK3CA | |
| SCHEMBL27785951 | 0.85 | CRHR1 (0.41) | GABRG2GABRB3GABRA2NPY1RNPY5R | |
| SCHEMBL27786017 | 0.85 | ALK (0.35) | GABRG2GABRB3GABRA2NPY1RNPY5R | |
| SCHEMBL27786270 | 0.83 | GABRG2 (0.41) | GABRG2GABRB3GABRA2 | |
| SCHEMBL27807904 | 0.83 | PIK3CA (0.42) | PIK3CAMTOR | |
| SCHEMBL27785925 | 0.83 | GABRA2 (0.36) | GABRG2GABRB3GABRA2PIK3CAMTOR | |
| SCHEMBL27785957 | 0.82 | PIK3CA (0.39) | GABRG2GABRB3GABRA2PIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | claimed |
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |