Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568554 | 0.87 | TRPA1 (0.38) | TRPA1MAPTKDM4ELMNANOS3 | |
| SCHEMBL2866347 | 0.80 | MAOA (0.45) | TRPA1MAPTKDM4ENOS3NOS1 | |
| SCHEMBL19690478 | 0.79 | TRPA1 (0.51) | TRPA1MAPTKDM4ETSHRALOX15 | |
| SCHEMBL11036381 | 0.78 | NOS3 (0.37) | TRPA1MAPTKDM4ENOS3NOS1 | |
| Potassium Ion SCHEMBL10910684 | 0.78 | NOS3 (0.37) | TRPA1MAPTKDM4ENOS3NOS1 | |
| SCHEMBL2783069 | 0.76 | NOS3 (0.36) | TRPA1MAPTKDM4ENOS3NOS1 | |
| SCHEMBL11371357 | 0.75 | ALDH1A1 (0.45) | TRPA1MAPTKDM4ETSHRGAA | |
| SCHEMBL6176098 | 0.75 | TRPA1 (0.40) | TRPA1MAPTKDM4EGAALMNA | |
| SCHEMBL11375227 | 0.74 | TRPA1 (0.39) | TRPA1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5827434 | 0.73 | NOS3 (0.39) | TRPA1MAPTKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070449-A2 | HIGHLY PURE LAQUINIMOD OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ACTAVIS GROUP PTC EHF (IS) | 2010-06-24 | — | — | WO | disclosed |