Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 15/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776285 | 0.76 | ADRA1A (0.54) | ADRA1AADRA2AADRA1DADRA1BCYP2D6 | |
| SCHEMBL9814143 | 0.76 | ADRA1A (0.70) | ADRA1AADRA2AADRA1DADRA1BCYP2D6 | |
| Hydrochloric Acid SCHEMBL10756176 | 0.75 | ADRA1A (0.69) | ADRA1AADRA2AADRA1DADRA1BCYP2D6 | |
| SCHEMBL769219 | 0.73 | ADRA1A (0.53) | ADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL769101 | 0.71 | ADRA1A (1.00) | ADRA1AADRA2AADRA1DADRA1BCYP2D6 | |
| SCHEMBL14969050 | 0.70 | ADRA1A (0.65) | ADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL14968990 | 0.70 | ADRA1A (0.63) | ADRA1AADRA2AADRA1DADRA1BCYP2D6 | |
| SCHEMBL11478213 | 0.70 | UGT2B17 (0.46) | CYP2D6HTR2A | |
| SCHEMBL2774645 | 0.68 | ADRA2A (0.53) | ADRA1AADRA2AADRA1DADRA1B | |
| SCHEMBL2790488 | 0.68 | CYP2D6 (0.44) | ADRA1AADRA2AADRA1DADRA1BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1499609-A4 | PESTICIDAL HETEROCYCLES | FMC CORP (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050143418-A1 | Pesticidal heterocycles | FMC CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1499609-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092374-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | DDT, CBR3, ACHE | ADRA1A 1130/4885ADRA2A 1935/4885ADRA1D 1129/4885 |
| US-20050143418-A1 | Pesticidal heterocycles | DDT, TRHR, ACHE | ADRA1A 974/4885ADRA2A 1884/4885ADRA1D 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.