Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 9/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2790488 | 0.73 | CYP2D6 (0.44) | ADRA2AADRA1AADRA1DADRA1B | |
| SCHEMBL31140107 | 0.70 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL31140093 | 0.70 | ADRA2A (0.60) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL2779092 | 0.68 | ADRA1A (0.54) | ADRA2AADRA1AADRA1DADRA1B | |
| SCHEMBL19594955 | 0.67 | CA1 (0.51) | — | |
| SCHEMBL2776426 | 0.66 | NQO2 (0.43) | CYP19A1 | |
| SCHEMBL2776285 | 0.66 | ADRA1A (0.54) | ADRA2AADRA1AADRA1DADRA1B | |
| SCHEMBL7943729 | 0.64 | CYP19A1 (1.00) | CYP19A1CYP11B2 | |
| SCHEMBL11478213 | 0.64 | UGT2B17 (0.46) | — | |
| SCHEMBL7848778 | 0.64 | MAOA (0.79) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767667-B2 | Pesticidal heterocycles | FMC CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | BAYER CROPSCIENCE AG (DE) | 2009-01-08 | — | — | US | disclosed |
| US-7417057-B2 | Pesticidal heterocycles | BAYER CROPSCIENCE AG (DE) | 2008-08-26 | — | — | US | disclosed |
| EP-1499609-A4 | PESTICIDAL HETEROCYCLES | FMC CORP (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20050143418-A1 | Pesticidal heterocycles | FMC CORPORATION | 2005-06-30 | — | — | US | disclosed |
| EP-1499609-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003092374-A2 | PESTICIDAL HETEROCYCLES | FMC CORPORATION (US) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012070-A1 | PESTICIDAL HETEROCYCLES | DDT, CBR3, ACHE | ADRA2A 1935/4885ADRA2B 1213/4885ADRA2C 560/4885 |
| US-20050143418-A1 | Pesticidal heterocycles | DDT, TRHR, ACHE | ADRA2A 1884/4885ADRA2B 1224/4885ADRA2C 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.