Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27791062 | 0.86 | CHRNB2 (0.32) | AXLINSRKDR | |
| SCHEMBL467580 | 0.82 | AXL (0.36) | AXLINSRKDR | |
| SCHEMBL27790975 | 0.81 | AXL (0.47) | AXLINSRKDR | |
| SCHEMBL30090809 | 0.81 | AXL (0.47) | AXLINSRKDR | |
| SCHEMBL467579 | 0.80 | — | — | |
| SCHEMBL467659 | 0.78 | AXL (0.49) | AXLINSRKDR | |
| SCHEMBL467833 | 0.77 | AXL (0.47) | AXLINSRKDR | |
| SCHEMBL467792 | 0.76 | AXL (0.44) | AXLINSRKDR | |
| SCHEMBL467688 | 0.75 | AXL (0.40) | AXLINSRKDR | |
| SCHEMBL467601 | 0.74 | FLT3 (0.36) | AXLINSRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101622246-A | Polycyclic heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2010-01-06 | — | — | CN | claimed |
| CN-101622246-A | Polycyclic heteroaryl substituted triazoles useful as AXL inhibitors | RIGEL PHARMACEUTICALS INC | 2010-01-06 | — | — | CN | disclosed |