Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27771290 | 0.77 | NPC1 (0.64) | RAB9ANPC1TP53GAAMITF | |
| SCHEMBL27792368 | 0.77 | KCNMA1 (0.74) | RAB9ANPC1TP53GAAKDM4E | |
| SCHEMBL27771238 | 0.76 | MAOB (0.54) | RAB9ANPC1TP53GAAMITF | |
| SCHEMBL27771282 | 0.75 | PKM (0.63) | RAB9ANPC1TP53GAAKDM4E | |
| SCHEMBL4865759 | 0.75 | RAB9A (0.58) | RAB9ANPC1TP53GAAMITF | |
| SCHEMBL9976445 | 0.75 | RAB9A (0.57) | RAB9ANPC1TP53GAAMITF | |
| SCHEMBL25143173 | 0.75 | NPC1 (0.74) | RAB9ANPC1TP53GAAMITF | |
| SCHEMBL31665320 | 0.75 | NPC1 (0.74) | RAB9ANPC1TP53GAAMITF | |
| SCHEMBL10178023 | 0.74 | F10 (0.64) | — | |
| SCHEMBL14885955 | 0.74 | TMPRSS4 (0.74) | RAB9ANPC1ALDH1A1SMN1; SMN2SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |