SCHEMBL2779285

SCHEMBL2779285

O=C(O)c1[c]ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
ALOX15 P16050 1/20 0.37
CYP1A2 P05177 1/20 0.37
AKR1C3 P42330 1/20 0.34
CA12 O43570 4/20 0.33
CA1 P00915 4/20 0.33
CA2 P00918 4/20 0.33
CA7 P43166 4/20 0.33
CA9 Q16790 4/20 0.33
CA14 Q9ULX7 4/20 0.33
KDM4E B2RXH2 3/20 0.32
KMT2A Q03164 1/20 0.32
HMGB1 P09429 1/20 0.32
HPGD P15428 1/20 0.32
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
SELL P14151 1/20 0.31
SELP P16109 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6633438 0.78 CA12 (0.48) ALDH1A1CA12CA1CA2CA7
SCHEMBL6633958 0.78 CA1 (0.38) ALDH1A1ALOX15CYP1A2AKR1C3CA12
SCHEMBL6631347 0.78 SELL (0.45) ALDH1A1ALOX15CYP1A2CA12CA1
SCHEMBL8641020 0.77 TDP1 (0.38) ALDH1A1CA12CA1CA2CA7
SCHEMBL8644706 0.77 KDM4E (0.38) ALDH1A1ALOX15CYP1A2AKR1C3KDM4E
SCHEMBL7771345 0.77 KMT2A (0.39) ALDH1A1ALOX15CYP1A2AKR1C3KDM4E
SCHEMBL6718464 0.72 CA1 (0.41) ALDH1A1ALOX15CA12CA1CA2
SCHEMBL6630726 0.72 ALDH1A1 (0.36) ALDH1A1ALOX15CYP1A2AKR1C3CA1
SCHEMBL6630725 0.72 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2HSD17B10TSHR
SCHEMBL8529933 0.72 ALDH1A1 (0.43) ALDH1A1ALOX15CYP1A2AKR1C3CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117695256-A Preparation method of functional lutein compound and application of functional lutein compound in relieving xerophthalmia 大连工业大学 2024-03-15 CN claimed
CN-115005536-B Seamless line-pressing type down jacket fabric and preparation method thereof 高梵(浙江)信息技术有限公司 2023-09-26 CN claimed
CN-114940825-B Mirror silica gel and preparation method thereof 凤阳加松新型材料科技有限公司 2023-07-21 CN claimed
CN-113650390-B Preparation method of antibacterial anti-fouling fabric 高梵(浙江)信息技术有限公司 2023-06-06 CN claimed
CN-115195179-B Seamless line-pressing type down jacket manufacturing equipment and process 高梵(浙江)信息技术有限公司 2023-06-02 CN claimed
US-20200347248-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ENVISTA (US) 2020-11-05 US claimed
US-20200347247-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ENVISTA (US) 2020-11-05 US claimed
US-10689407-B2 Photo-cleavable primer compositions and methods of use ENVISTA (US) 2020-06-23 US claimed
EP-3408253-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE Acatechol, Inc. (US) 2018-12-05 EP claimed
EP-3408272-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE Acatechol, Inc. (US) 2018-12-05 EP claimed
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US claimed
WO-2017132484-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ACatechol, Inc. (US) 2017-08-03 WO claimed
WO-2017132463-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE ACatechol, Inc. (US) 2017-08-03 WO claimed
US-20170217997-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE ORMCO CORPORATION 2017-08-03 US claimed
US-8975259-B2 Compositions and methods for inhibiting G protein signaling UNIVERSITY OF ROCHESTER (US) 2015-03-10 US claimed
US-20100130505-A1 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING UNIVERSITY OF ROCHESTER (US) 2010-05-27 US claimed
EP-2147310-A2 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING University of Rochester (US) 2010-01-27 EP claimed
WO-2009020677-A9 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING UNIV ROCHESTER (US) 2009-04-16 WO claimed
WO-2009020677-A2 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING UNIVERSITY OF ROCHESTER (US) 2009-02-12 WO claimed
US-20060049052-A1 Ampholytic buffer having high buffering capacity and high conductivity in isoelectric form THE TEXAS A&M UNIVERSITY SYSTEM (US) 2006-03-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217999-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 ALDH1A1 1177/4885ALOX15 3081/4885CYP1A2 2409/4885
US-20200347247-A1 SURFACE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, GRIN1 ALDH1A1 1177/4885ALOX15 3081/4885CYP1A2 2409/4885
US-20200347248-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, ESR1 ALDH1A1 869/4885ALOX15 1816/4885CYP1A2 1386/4885
US-20170217997-A1 PHOTO-CLEAVABLE PRIMER COMPOSITIONS AND METHODS OF USE SP1, GPER1, ESR1 ALDH1A1 869/4885ALOX15 1816/4885CYP1A2 1386/4885
US-20060049052-A1 Ampholytic buffer having high buffering capacity and high conductivity in isoelectric form ALPP, CA2, CA1 ALDH1A1 4582/4885ALOX15 4140/4885CYP1A2 4830/4885
US-20100130505-A1 COMPOSITIONS AND METHODS FOR INHIBITING G PROTEIN SIGNALING GNAI1, GNAI3, GNAI2 ALDH1A1 4720/4885ALOX15 3602/4885CYP1A2 4839/4885
US-10689407-B2 Photo-cleavable primer compositions and methods of use SP1, GPER1, ESR1 ALDH1A1 869/4885ALOX15 1816/4885CYP1A2 1386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.