Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ACR | P10323 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27794706 | 0.93 | ALPL (0.37) | LMNAPTPN1GAARAB9ACYP2C19 | |
| SCHEMBL27815832 | 0.93 | MAPT (0.37) | LMNAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL28788347 | 0.88 | ALPL (0.37) | TP53L3MBTL1RAB9APOLBMEN1 | |
| SCHEMBL27963119 | 0.79 | LMNA (0.45) | LMNAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL27963122 | 0.73 | MME (0.42) | LMNARAB9AMEN1NPC1MAPT | |
| SCHEMBL27963175 | 0.72 | CYP11B1 (0.38) | LMNAADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL27963148 | 0.72 | MAPT (0.39) | LMNAPTPN1CYP11B1CYP11B2RAB9A | |
| SCHEMBL28013858 | 0.68 | NPC1 (0.47) | LMNATP53L3MBTL1GAACYP11B1 | |
| SCHEMBL27963121 | 0.68 | MAPT (0.42) | TP53L3MBTL1RAB9APOLBMEN1 | |
| SCHEMBL28013861 | 0.68 | ALPL (0.40) | L3MBTL1RETRAB9ACYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101870676-B | 1-(2-oximido-2-phenylethyl)-3-phenyl-1H-pyrazol-5-ethyl formate derivative as well as preparation method and application thereof | UNIV SHANDONG | 2011-09-07 | — | — | CN | disclosed |
| CN-101870676-A | 1-(2-oximido-2-phenylethyl)-3-phenyl-1H-pyrazol-5-ethyl formate derivative as well as preparation method and application thereof | UNIV SHANDONG | 2010-10-27 | — | — | CN | disclosed |