Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27795300 | 0.86 | UTS2R (0.48) | UTS2RMAPT | |
| SCHEMBL27952278 | 0.85 | LMNA (0.40) | UTS2R | |
| SCHEMBL27955103 | 0.85 | MAPT (0.44) | UTS2RMAPT | |
| SCHEMBL27816303 | 0.82 | UTS2R (0.44) | UTS2RMAPT | |
| SCHEMBL27952296 | 0.82 | PKM (0.43) | UTS2R | |
| SCHEMBL27836333 | 0.76 | SLC6A2 (0.40) | MAPT | |
| SCHEMBL28995697 | 0.75 | RAB9A (0.40) | UTS2RMAPT | |
| SCHEMBL28821222 | 0.75 | TSHR (0.42) | UTS2RMAPT | |
| SCHEMBL2998886 | 0.74 | LMNA (0.45) | MAPT | |
| SCHEMBL28404198 | 0.74 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103635472-A | Serine/threonine kinase inhibitors | ARRAY BIOPHARMA INC | 2014-03-12 | — | — | CN | disclosed |
| CN-101861321-B | Pyrrolo [2, 3 -D] pyrimidin derivatives as protein kinase B inhibitors | ASTRAZENECA AB | 2013-02-06 | — | — | CN | disclosed |
| CN-101861321-A | Pyrrolo [2, 3 -D] pyrimidin derivatives as protein kinase B inhibitors | ASTRAZENECA AB | 2010-10-13 | — | — | CN | disclosed |