Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821222 | 0.87 | TSHR (0.42) | ALDH1A1LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28995697 | 0.87 | RAB9A (0.40) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL27674503 | 0.85 | LMNA (0.39) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL27674502 | 0.85 | LMNA (0.39) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL28862367 | 0.85 | MAPT (0.47) | KMT2ANPC1RAB9AMEN1LMNA | |
| SCHEMBL29199783 | 0.84 | NPSR1 (0.46) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL27571172 | 0.84 | NPSR1 (0.46) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL28764261 | 0.83 | ALDH1A1 (0.40) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL28069939 | 0.83 | ALDH1A1 (0.40) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL25222548 | 0.81 | KMT2A (0.47) | KMT2ANPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218859-A | Modulators of proteolysis and related methods of use | 阿尔维纳斯运营股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| CN-111212835-A | Compounds and methods for targeted degradation of androgen receptors | 阿尔维纳斯运营股份有限公司 | 2020-05-29 | — | — | CN | disclosed |