Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28821222 | 0.88 | TSHR (0.42) | SMN1; SMN2UTS2RALDH1A1LMNAMAPT | |
| SCHEMBL27674502 | 0.87 | LMNA (0.39) | SMN1; SMN2MMP1MMP3ALDH1A1LMNA | |
| SCHEMBL27674503 | 0.87 | LMNA (0.39) | SMN1; SMN2MMP1MMP3ALDH1A1LMNA | |
| SCHEMBL28404198 | 0.87 | KMT2A (0.43) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL28862367 | 0.86 | MAPT (0.47) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL29199783 | 0.85 | NPSR1 (0.46) | RAB9ASMN1; SMN2NPC1HPGDTNF | |
| SCHEMBL27571172 | 0.85 | NPSR1 (0.46) | RAB9ASMN1; SMN2NPC1HPGDTNF | |
| SCHEMBL27888280 | 0.82 | CNR2 (0.49) | RAB9ANPC1UTS2RALDH1A1MAPT | |
| SCHEMBL28619569 | 0.82 | RORC (0.39) | LMNA | |
| SCHEMBL29287118 | 0.78 | SLC6A9 (0.37) | MMP2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916790-A | Pyrido [2,3-b ] [1,4] oxazines or tetrahydropyrido [2,3-b ] [1,4] oxazepines as IAP antagonists | 百济神州有限公司 | 2023-04-04 | — | — | CN | disclosed |