Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resorcinol SCHEMBL27796353 | 0.76 | MAOA (0.53) | NPC1RAB9AALDH1A1MMP1MMP2 | |
| SCHEMBL19403902 | 0.75 | HDAC1 (0.79) | HDAC1HDAC2HDAC6NPC1RAB9A | |
| SCHEMBL27782781 | 0.74 | CXCR1 (0.54) | HDAC1HDAC2HDAC6NPC1RAB9A | |
| Cinnamaldehyde SCHEMBL5390536 | 0.72 | CDK4 (0.79) | ALDH1A1MMP1MMP2MMP9SMN1; SMN2 | |
| Cinnamaldehyde SCHEMBL21404274 | 0.72 | CDK4 (0.79) | ALDH1A1MMP1MMP2MMP9SMN1; SMN2 | |
| SCHEMBL19398196 | 0.72 | ALDH1A1 (0.61) | HDAC1HDAC2HDAC6NPC1RAB9A | |
| SCHEMBL22284093 | 0.72 | ALDH1A1 (0.61) | HDAC1HDAC2HDAC6NPC1RAB9A | |
| SCHEMBL9321550 | 0.72 | CCNB2 (0.61) | ALDH1A1MMP1MMP2MMP9MAPT | |
| SCHEMBL9321558 | 0.72 | CCNB2 (0.61) | ALDH1A1MMP1MMP2MMP9MAPT | |
| Resorcinol SCHEMBL27796352 | 0.72 | MMP1 (0.58) | HDAC1HDAC2HDAC6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | claimed |
| CN-101880246-B | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-03 | — | — | CN | disclosed |
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | disclosed |