Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 2/20 | 0.58 |
| ▸ | MMP9 | P14780 | 2/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.48 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.48 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.48 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.48 |
| ▸ | SPR | P35270 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27599897 | 0.89 | EPHX1 (0.66) | MMP1MMP2MMP9EPHX1NPC1 | |
| SCHEMBL22588919 | 0.79 | KMT2A (0.72) | TRPV1EPHX1NPC1RAB9AMAPT | |
| SCHEMBL14087170 | 0.78 | MTNR1A (0.50) | EPHX1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL6032606 | 0.77 | EPHX1 (0.85) | MMP1MMP2EPHX1NPC1RAB9A | |
| Resorcinol SCHEMBL27796353 | 0.75 | MAOA (0.53) | MMP1MMP2MMP9TRPV1EPHX1 | |
| SCHEMBL2749289 | 0.74 | SPR (0.63) | MMP1MMP2MMP9TRPV1NPC1 | |
| SCHEMBL18114812 | 0.74 | OPRK1 (0.62) | SLC6A5OPRD1OPRK1TAAR1OPRM1 | |
| SCHEMBL17117307 | 0.74 | EPHX2 (0.80) | EPHX1NPC1RAB9AMAPTKMT2A | |
| Resorcinol SCHEMBL4639098 | 0.73 | OPRK1 (0.64) | OPRD1OPRK1ALDH1A1TAAR1CA12 | |
| SCHEMBL5724291 | 0.73 | CA1 (0.69) | NPC1RAB9AMEN1KMT2ASPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | claimed |
| CN-101880246-B | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2012-10-03 | — | — | CN | disclosed |
| CN-101880246-A | Substituted benzoyl urea compound and preparation method and application thereof | SHANGHAI INST MATERIA MEDICA | 2010-11-10 | — | — | CN | disclosed |