Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2336929 | 0.86 | MRGPRX4 (0.54) | RAB9AGPBAR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2780412 | 0.85 | UGCG (0.49) | RAB9AGPBAR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2335696 | 0.85 | GPBAR1 (0.60) | RAB9AGPBAR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2784871 | 0.84 | TTR (0.50) | RAB9AGPBAR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2336930 | 0.84 | LMNA (0.47) | RAB9AGPBAR1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2779965 | 0.82 | ROCK2 (0.46) | RAB9AGPBAR1NPC1SMN1; SMN2LMNA | |
| SCHEMBL2782226 | 0.81 | TAS2R14 (0.48) | RAB9ASMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL2780235 | 0.79 | PTGER1 (0.48) | RAB9AGPBAR1SMN1; SMN2LMNAPOLB | |
| SCHEMBL2779334 | 0.77 | RAB9A (0.76) | RAB9ASMN1; SMN2LMNAALDH1A1GAA | |
| SCHEMBL2779685 | 0.77 | MRGPRX4 (0.47) | RAB9AGPBAR1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010091104-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | EXELIXIS, INC. (US) | 2010-08-12 | — | — | WO | disclosed |