Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28782801 | 0.91 | RXRA (0.44) | MDM2RXRAGRIN1GRIN2BKCNH2 | |
| SCHEMBL28782751 | 0.85 | ABCB11 (0.51) | P2RX7CCR2 | |
| SCHEMBL2661992 | 0.85 | PTGER4 (0.39) | FFAR1MDM2PTGER4PDE2AKIF11 | |
| SCHEMBL27776347 | 0.83 | CCR2 (0.41) | MDM2PTGER4CCR2 | |
| SCHEMBL27776345 | 0.83 | CCR9 (0.44) | PTGER4CCR2 | |
| SCHEMBL27776162 | 0.81 | CA12 (0.41) | CCR2 | |
| SCHEMBL27776196 | 0.81 | P2RX7 (0.43) | PPARGP2RX7CCR2 | |
| SCHEMBL2661487 | 0.81 | RXRA (0.41) | MDM2RXRAGRIN1GRIN2BP2RX7 | |
| SCHEMBL27776179 | 0.80 | PTGER4 (0.48) | PTGER4RXRAGRIN1GRIN2B | |
| SCHEMBL27776172 | 0.78 | CYP2D6 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679365-A | As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE L | 2010-03-24 | — | — | CN | claimed |
| CN-101679365-A | As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE L | 2010-03-24 | — | — | CN | disclosed |