Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27797356 | 0.91 | FFAR1 (0.40) | RXRAGRIN1GRIN2BMDM2P2RX7 | |
| SCHEMBL2661487 | 0.90 | RXRA (0.41) | RXRAGRIN1GRIN2BARLMNA | |
| SCHEMBL28782751 | 0.87 | ABCB11 (0.51) | ABCB11P2RX7CCR2 | |
| SCHEMBL2661784 | 0.85 | AR (0.41) | RXRAGRIN1GRIN2BARLMNA | |
| SCHEMBL2661623 | 0.84 | LMNA (0.42) | RXRAGRIN1GRIN2BARLMNA | |
| SCHEMBL27776196 | 0.83 | P2RX7 (0.43) | ABCB11P2RX7CCR2 | |
| SCHEMBL27776345 | 0.83 | CCR9 (0.44) | MAPTCCR2 | |
| SCHEMBL28785588 | 0.81 | VNN1 (0.43) | RXRAGRIN1GRIN2BLMNATP53 | |
| SCHEMBL27776162 | 0.81 | CA12 (0.41) | TP53CCR2 | |
| SCHEMBL27776347 | 0.81 | CCR2 (0.41) | ABCB11MDM2CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679365-A | As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE L | 2010-03-24 | — | — | CN | claimed |
| CN-101679365-A | As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE L | 2010-03-24 | — | — | CN | disclosed |