SCHEMBL27798157

SCHEMBL27798157

NC(=O)c1ccc(C(N)=O)c(-c2c(O)c(O)cc3c2-c2ccccc2-3)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.38
PDK2 Q15119 2/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
LCK P06239 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TTR P02766 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSPD1 P10809 1/20 0.36
ALOX15 P16050 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27597015 0.79 KEAP1 (0.47) BCAT2PDK2KEAP1NFE2L2KDM4E
SCHEMBL9505602 0.79 PARP1 (0.44) BCAT2PDK2KEAP1NFE2L2KDM4E
SCHEMBL7052546 0.78 KEAP1 (0.46) BCAT2PDK2KEAP1NFE2L2MAPT
Water SCHEMBL27919080 0.78 KEAP1 (0.46) BCAT2PDK2KEAP1NFE2L2KDM4E
SCHEMBL29400809 0.72 BCAT2 (0.47) BCAT2PDK2MEN1KMT2AL3MBTL1
SCHEMBL17907467 0.71 PARP1 (0.50) PARP1ARHTR7HTR2B
SCHEMBL27621512 0.71 BTK (0.50) BCAT2PDK2ALDH1A1MAPTHSD17B10
Terephthalamide SCHEMBL27742428 0.71 MAPT (0.47) PDK2KEAP1NFE2L2KDM4EALDH1A1
SCHEMBL7114095 0.71 L3MBTL1 (0.59) PDK2MAPTHSD17B10TSHRLCK
SCHEMBL3265708 0.71 BCAT2 (0.63) BCAT2MAPTHSD17B10TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101687988-A Polybenzazole and polybenzazole precursor TEIJIN ARAMID BV 2010-03-31 CN disclosed