Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597015 | 0.93 | KEAP1 (0.47) | PARP1KDM4EALDH1A1MAPTTSHR | |
| Water SCHEMBL27919080 | 0.91 | KEAP1 (0.46) | PARP1KDM4EALDH1A1MAPTTSHR | |
| Terephthalamide SCHEMBL27884071 | 0.85 | MAPT (0.48) | PARP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL7052546 | 0.82 | KEAP1 (0.46) | PARP1MAPTTSHRHSD17B10KEAP1 | |
| SCHEMBL9711413 | 0.81 | PDK2 (0.45) | PARP1MAPTTSHRHSD17B10KEAP1 | |
| SCHEMBL27581201 | 0.80 | PARP1 (0.40) | PARP1MAPTTSHRHSD17B10KEAP1 | |
| SCHEMBL27798157 | 0.79 | BCAT2 (0.38) | PARP1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL27621512 | 0.75 | BTK (0.50) | PARP1ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL1460367 | 0.75 | KDM4E (0.46) | PARP1KDM4EALDH1A1HPGDBCAT2 | |
| SCHEMBL25223943 | 0.74 | GRM2 (0.46) | PARP1MAPTTSHRHSD17B10BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0189189-B1 | FLEXIBLE SHEET REINFORCED WITH POLY(AROMATIC AMIDE) NON-WOVEN FABRIC AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5049435-A | Printed circuits | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1991-09-17 | — | — | US | disclosed |
| US-4897301-A | DIMENSIONAL STABILITY, HEAT RESISTANCE, DIELECTRICS | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0189189-A2 | Flexible sheet reinforced with poly(aromatic amide) non-woven fabric and use thereof | Toyo Boseki Kabushiki Kaisha (JP) | 1986-07-30 | — | — | EP | disclosed |