SCHEMBL7052546

SCHEMBL7052546

NC(=O)c1ccc(C(N)=O)c(-c2ccc(C(N)=O)c3c2-c2ccccc2-3)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.43
BCAT2 O15382 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
PDK2 Q15119 3/20 0.42
PARP1 P09874 2/20 0.41
CSNK1A1 P48729 1/20 0.39
TYRO3 Q06418 1/20 0.39
DYRK1B Q9Y463 1/20 0.39
GRK6 P43250 1/20 0.39
POLB P06746 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.38
CYP2C19 P33261 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27597015 0.89 KEAP1 (0.47) KEAP1NFE2L2L3MBTL1BCAT2MEN1
Water SCHEMBL27919080 0.87 KEAP1 (0.46) KEAP1NFE2L2L3MBTL1BCAT2MEN1
SCHEMBL9505602 0.82 PARP1 (0.44) KEAP1NFE2L2L3MBTL1BCAT2MEN1
SCHEMBL41435 0.80 KEAP1 (0.64) KEAP1NFE2L2L3MBTL1BCAT2KMT2A
SCHEMBL27621512 0.80 BTK (0.50) L3MBTL1BCAT2MEN1KMT2APDK2
SCHEMBL25223943 0.79 GRM2 (0.46) L3MBTL1BCAT2MEN1KMT2APDK2
SCHEMBL27798157 0.78 BCAT2 (0.38) KEAP1NFE2L2L3MBTL1BCAT2MEN1
SCHEMBL29400809 0.77 BCAT2 (0.47) L3MBTL1BCAT2MEN1KMT2APDK2
SCHEMBL9711413 0.77 PDK2 (0.45) KEAP1NFE2L2L3MBTL1BCAT2PDK2
SCHEMBL7114095 0.77 L3MBTL1 (0.59) L3MBTL1MEN1KMT2APDK2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299482-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING FIBRES AND METAL-CONTAINING CO-POLYMERS J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2003-04-09 EP disclosed
EP-1208167-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2002-05-29 EP disclosed
EP-1203057-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION CONTAINING BLOCKED ACID FUNCTIONAL CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2002-05-08 EP disclosed
WO-2001094479-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING FIBRES AND METAL-CONTAINING CO-POLYMERS J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2001-12-13 WO disclosed
WO-2000077103-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION CONTAINING BLOCKED ACID FUNCTIONAL CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2000-12-21 WO disclosed
WO-2000077102-A1 SELF-POLISHING MARINE ANTIFOULING PAINT COMPOSITION COMPRISING SILICON-CONTAINING CO-POLYMERS AND FIBRES J.C. HEMPEL'S SKIBSFARVE-FABRIK A/S (DK) 2000-12-21 WO disclosed