Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ACACA | Q13085 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533772 | 0.90 | L3MBTL1 (0.62) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL21247766 | 0.84 | L3MBTL1 (0.53) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL434623 | 0.84 | L3MBTL1 (0.53) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL4600135 | 0.80 | ALDH1A1 (0.62) | KMT2AALDH1A1MEN1KDM4ETSHR | |
| SCHEMBL29869842 | 0.80 | ALDH1A1 (0.58) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL505528 | 0.80 | ALDH1A1 (0.58) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL16541896 | 0.80 | PDE4A (0.57) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL27684154 | 0.80 | PDE4A (0.54) | L3MBTL1NPC1RAB9AHPGDERN1 | |
| SCHEMBL8840880 | 0.79 | PDE4A (0.67) | L3MBTL1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7218179 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDTSHRERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101863867-B | Derivatives of flavonoids compounds and preparation method and application thereof | UNIV TSINGHUA GRADUATE SCHOOL | 2012-07-18 | — | — | CN | disclosed |
| CN-101863867-A | Derivatives of flavonoids compounds and preparation method and application thereof | UNIV TSINGHUA GRADUATE SCHOOL | 2010-10-20 | — | — | CN | disclosed |