SCHEMBL434623

SCHEMBL434623

COc1ccc(-c2ccccc2)cc1OC.N=C=O.N=C=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
KMT2A Q03164 3/20 0.51
ALDH1A1 P00352 3/20 0.51
HPGD P15428 3/20 0.51
KDM4E B2RXH2 2/20 0.51
MEN1 O00255 2/20 0.51
USP2 O75604 1/20 0.51
TSHR P16473 1/20 0.51
MAPK1 P28482 1/20 0.51
HTT P42858 1/20 0.51
ATM Q13315 1/20 0.51
HSD17B10 Q99714 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
ACACA Q13085 1/20 0.48
PDE4A P27815 3/20 0.47
PDE4B Q07343 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21247766 1.00 L3MBTL1 (0.53) L3MBTL1NPC1RAB9AKMT2AALDH1A1
SCHEMBL4533772 0.89 L3MBTL1 (0.62) L3MBTL1NPC1RAB9AKMT2AALDH1A1
Acetaldehyde SCHEMBL27798693 0.84 L3MBTL1 (0.54) L3MBTL1NPC1RAB9AKMT2AALDH1A1
SCHEMBL5255563 0.80 MAOA (0.49) L3MBTL1NPC1RAB9AKMT2AALDH1A1
SCHEMBL30196061 0.79 KDM4E (0.52) L3MBTL1NPC1RAB9AKMT2AALDH1A1
SCHEMBL16541896 0.78 PDE4A (0.57) L3MBTL1NPC1RAB9AKMT2AALDH1A1
1,2-Dimethoxybenzene SCHEMBL27809980 0.78 CA1 (0.68) L3MBTL1KMT2AALDH1A1TSHRMAPK1
1,2-Dimethoxybenzene SCHEMBL21247641 0.78 CA1 (0.68) L3MBTL1KMT2AALDH1A1TSHRMAPK1
SCHEMBL8840880 0.78 PDE4A (0.67) L3MBTL1NPC1RAB9AKMT2AALDH1A1
SCHEMBL8678736 0.77 PDE4A (0.50) L3MBTL1NPC1RAB9AKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140190690-A1 OIL FORMULATION FOR PREVENTING WATER PENETRATION IN UNDERGROUND FORMATIONS RHODIA OPERATIONS (FR) 2014-07-10 US claimed
EP-2164920-B1 OIL FORMULATION FOR PREVENTING WATER PENETRATION IN UNDERGROUND FORMATIONS RHODIA OPERATIONS (FR) 2011-10-26 EP claimed
US-20100210485-A1 Oil Formulation for Preventing Water Penetration in Underground Formations RHODIA OPERATIONS (FR) 2010-08-19 US claimed
EP-2164920-A1 OIL FORMULATION FOR PREVENTING WATER PENETRATION IN UNDERGROUND FORMATIONS Rhodia Opérations (FR) 2010-03-24 EP claimed
WO-2009003857-A1 OIL FORMULATION FOR PREVENTING WATER PENETRATION IN UNDERGROUND FORMATIONS RHODIA OPERATIONS (FR) 2009-01-08 WO claimed
EP-3353223-A1 COPOLYMER POLYOL WITH FUNCTIONAL ADDITIVE IN DISPERSED PHASE Dow Global Technologies LLC (US) 2018-08-01 EP disclosed
WO-2017053064-A1 COPOLYMER POLYOL WITH FUNCTIONAL ADDITIVE IN DISPERSED PHASE DOW GLOBAL TECHNOLOGIES LLC (US) 2017-03-30 WO disclosed
US-20140190690-A1 OIL FORMULATION FOR PREVENTING WATER PENETRATION IN UNDERGROUND FORMATIONS RHODIA OPERATIONS (FR) 2014-07-10 US disclosed
EP-2596038-A1 REDUCTION IN MODULUS OF POLYURETHANE SEALANTS AND ADHESIVES Construction Research & Technology GmbH (DE) 2013-05-29 EP disclosed
WO-2012010558-A1 REDUCTION IN MODULUS OF POLYURETHANE SEALANTS AND ADHESIVES CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2012-01-26 WO disclosed
EP-2164920-B1 OIL FORMULATION FOR PREVENTING WATER PENETRATION IN UNDERGROUND FORMATIONS RHODIA OPERATIONS (FR) 2011-10-26 EP disclosed
US-20100210485-A1 Oil Formulation for Preventing Water Penetration in Underground Formations RHODIA OPERATIONS (FR) 2010-08-19 US disclosed
US-6660782-B1 By using a low molecular weight compound, such as propylene glycol, a substantially rigid polyurethane foam may be formed in the absence of a cross-linking polyol ESSEX SPECIALTY PRODUCTS, INC. 2003-12-09 US disclosed
EP-0418367-A4 SOLVENT RESISTANT POLYETHERPOLYURETHANE PRODUCTS AND PROCESS FOR PREPARING THE SAME 1991-10-23 EP disclosed
EP-0418367-A1 SOLVENT RESISTANT POLYETHERPOLYURETHANE PRODUCTS AND PROCESS FOR PREPARING THE SAME THE DOW CHEMICAL COMPANY (US) 1991-03-27 EP disclosed
WO-1990011310-A1 SOLVENT RESISTANT POLYETHERPOLYURETHANE PRODUCTS AND PROCESS FOR PREPARING THE SAME THE DOW CHEMICAL COMPANY (US) 1990-10-04 WO disclosed
EP-0333310-A2 Photographic support including a reflective layer FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed
EP-0293589-A1 Integral skin rigid polyurethane structural foam BASF Corporation (US) 1988-12-07 EP disclosed
EP-0270008-A2 Filled polyol compositions comprising stabilizers, polyurethanes prepared therefrom and processes for preparing the same THE DOW CHEMICAL COMPANY (US) 1988-06-08 EP disclosed
EP-0137489-A2 Polyisocyanurate foam prepared from an alkoxylated aromatic amine-aromatic polyester polyol blend THE CELOTEX CORPORATION (US) 1985-04-17 EP disclosed