SCHEMBL27801255

SCHEMBL27801255

CC(=O)OCCC1CNCCN1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
CHRM5 P08912 2/20 0.33
CHRM1 P11229 2/20 0.33
CHRM3 P20309 2/20 0.33
PGR P06401 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
HTR1A P08908 1/20 0.33
CHRNB2 P17787 1/20 0.33
TBXA2R P21731 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CHRNA10 Q9GZZ6 1/20 0.33
CHRNA9 Q9UGM1 1/20 0.33
TSHR P16473 1/20 0.33
GALR3 O60755 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26753792 1.00 ALDH1A1 (0.34) ALDH1A1CHRM5CHRM1CHRM3PGR
SCHEMBL27931637 0.86 CXCR4 (0.33) CXCR4SLC6A1GABRA5GABRB2SLC6A12
SCHEMBL5479801 0.84 THRB (0.40) ALDH1A1TSHR
SCHEMBL6305272 0.82 LTA4H (0.38) ALDH1A1LTA4HLMNAHSD17B10PARP1
Hydrochloric Acid SCHEMBL7418632 0.82 NAAA (0.36) CXCR4
SCHEMBL27958746 0.82 POLB (0.32) GAACXCR4
Hydrochloric Acid SCHEMBL28231371 0.81 LTA4H (0.37) ALDH1A1LTA4HLMNAHSD17B10PARP1
SCHEMBL6611392 0.79 MEN1 (0.40) CHRM1CHRM3CHRM2CHRNB2CHRNB4
SCHEMBL2796353 0.79 TSHR (0.42) ALDH1A1SMN1; SMN2TSHRCXCR4HSD17B10
SCHEMBL30277563 0.76 CXCR4 (0.43) CHRM4CHRNB2CHRNA3CHRNA4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115318113-B Nanofiltration membrane and preparation method and application thereof 清华大学 2023-10-31 CN disclosed
CN-115318113-A Nanofiltration membrane and preparation method and application thereof 清华大学 2022-11-11 CN disclosed
CN-103214473-A Dibenzo[b,f][1,4]oxazapine compounds ARYX THERAPEUTICS INC 2013-07-24 CN disclosed
CN-101641350-A Dibenzo [ b ] ARYX THERAPEUTICS INC US 2010-02-03 CN disclosed