Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL238951 | 0.87 | TSHR (0.50) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL27931637 | 0.82 | CXCR4 (0.33) | CXCR4 | |
| SCHEMBL26753792 | 0.79 | ALDH1A1 (0.34) | TSHRALDH1A1HSD17B10SMN1; SMN2CXCR4 | |
| SCHEMBL27801255 | 0.79 | ALDH1A1 (0.34) | TSHRALDH1A1HSD17B10SMN1; SMN2CXCR4 | |
| SCHEMBL5479801 | 0.77 | THRB (0.40) | TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL7418632 | 0.75 | NAAA (0.36) | CXCR4 | |
| SCHEMBL27958746 | 0.75 | POLB (0.32) | CXCR4 | |
| SCHEMBL28202519 | 0.74 | KMT2A (0.43) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL30277563 | 0.73 | CXCR4 (0.43) | SMN1; SMN2CXCR4 | |
| SCHEMBL11691124 | 0.73 | TSHR (0.40) | TSHRALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309669-B2 | Use of swellable polymer for sealing | EVONIK RÖHM GMBH (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20100163177-A1 | USE OF SWELLABLE POLYMER FOR SEALING | EVONIK ROEHM GMBH (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20040166080-A1 | Thermoplastic coating and binding agent for medicinal forms | ROEHM GBMH & CO. KG (DE) | 2004-08-26 | — | — | US | disclosed |
| US-5422121-A | Oral dosage unit form | ROHM GMBH (DE) | 1995-06-06 | — | — | US | disclosed |