Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305286 | 0.77 | CES2 (0.39) | CES2CES1ACHECA1CA2 | |
| SCHEMBL2539209 | 0.77 | ACHE (0.45) | CES2CES1ACHECA1CA2 | |
| SCHEMBL2154646 | 0.71 | — | — | |
| SCHEMBL196718 | 0.69 | CYP3A4 (0.44) | CES2CES1ACHECA1CA2 | |
| SCHEMBL780436 | 0.69 | HTR7 (0.37) | ACHEHTR7 | |
| SCHEMBL7606316 | 0.69 | ACHE (0.38) | ACHECA1CA2CA7CA9 | |
| SCHEMBL2153492 | 0.69 | NFE2L2 (0.41) | CES2CES1BCL2L1BADNPC1 | |
| SCHEMBL7933208 | 0.67 | CA1 (0.40) | CES2CES1ACHECA1CA2 | |
| SCHEMBL5713320 | 0.67 | CYP3A4 (0.42) | CES2CES1ACHECA1CA2 | |
| SCHEMBL6441401 | 0.67 | HTR7 (0.39) | CES2CES1ACHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104292453-A | Multi-sulfonated polyaromatic ether phosphine oxide high-molecular materials and preparation method and application thereof | UNIV TIANJIN NORMAL | 2015-01-21 | — | — | CN | disclosed |
| CN-101712756-B | Sulfonated polyether and phosphine oxide and preparation method thereof | UNIV TIANJIN NORMAL | 2012-01-25 | — | — | CN | disclosed |
| CN-101712756-A | Sulfonated polyether and phosphine oxide and preparation method thereof | UNIV TIANJIN NORMAL | 2010-05-26 | — | — | CN | disclosed |