SCHEMBL7606316

SCHEMBL7606316

CCP(C)c1ccc(F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.38
LMNA P02545 1/20 0.35
TRPA1 O75762 4/20 0.33
IDO1 P14902 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
ABCB11 O95342 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
HTR7 P34969 1/20 0.32
TAAR1 Q96RJ0 3/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15658057 0.77 ACHE (0.42) ACHELMNAIDO1TAAR1CA1
SCHEMBL7609754 0.74 PSMD14 (0.41) TRPA1HTR7HDAC3HDAC1HDAC2
SCHEMBL2782005 0.74 CYP3A4 (0.43) ACHELMNASIGMAR1TDP1
SCHEMBL2539209 0.73 ACHE (0.45) ACHELMNAIDO1LOXL2TAAR1
Bromide SCHEMBL8602057 0.72 CYP3A4 (0.41) ACHELMNATDP1
SCHEMBL15660608 0.71 LPL (0.43) TAAR1CA2L3MBTL1
SCHEMBL15658427 0.69 CA2 (0.47) ACHELMNACA1CA2
SCHEMBL6441401 0.68 HTR7 (0.39) ACHELMNAIDO1LOXL2HTR7
SCHEMBL7778608 0.67 TDP1 (0.36) ACHELMNATRPA1IDO1LOXL2
SCHEMBL196718 0.66 CYP3A4 (0.44) ACHEIDO1LOXL2TAAR1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed