Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.44 |
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967265 | 0.90 | MAPT (0.40) | PIK3CAMAPTALOX15 | |
| SCHEMBL27825633 | 0.87 | CASP1 (0.44) | MAPTALOX15 | |
| SCHEMBL27825621 | 0.86 | MAPT (0.35) | PIK3CAPIK3CBMAPTALOX15 | |
| SCHEMBL27805012 | 0.82 | ALDH1A1 (0.38) | KDRSYKMAPT | |
| SCHEMBL27805094 | 0.80 | NCF1 (0.34) | PIK3CAPIK3CBMAPTALOX15 | |
| SCHEMBL27804980 | 0.79 | MAPT (0.43) | KDRSYKGBA1CKS1BSKP1 | |
| SCHEMBL1124037 | 0.79 | PIK3CA (0.65) | PIK3CAGBA1PIK3CDPIK3R1PIK3CB | |
| SCHEMBL27825623 | 0.79 | CETP (0.36) | MAPT | |
| SCHEMBL27967345 | 0.77 | MAPT (0.40) | KDRSYKGBA1MAPT | |
| SCHEMBL28786910 | 0.75 | MAPT (0.47) | PIK3CAUSP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | claimed |
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | disclosed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |