Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27967345 | 0.95 | MAPT (0.40) | ALDH1A1MAPTLMNASLC6A2SLC6A4 | |
| SCHEMBL27967265 | 0.91 | MAPT (0.40) | MAPTLMNAMAPK1GFERGAA | |
| SCHEMBL27825633 | 0.88 | CASP1 (0.44) | MAPTKDM4EKMT2A | |
| SCHEMBL27825618 | 0.87 | SLC6A2 (0.35) | ALDH1A1MAPTLMNASLC6A2SLC6A4 | |
| SCHEMBL27805094 | 0.86 | NCF1 (0.34) | MAPTGFERSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27825621 | 0.85 | MAPT (0.35) | ALDH1A1MAPTLMNAMAPK1HPGD | |
| SCHEMBL27804977 | 0.82 | PIK3CA (0.48) | MAPTKDRSYK | |
| SCHEMBL27805003 | 0.81 | MAPT (0.42) | ALDH1A1MAPTLMNAMAPK1GFER | |
| SCHEMBL27967259 | 0.81 | NCF1 (0.37) | HRH1KCNH2 | |
| SCHEMBL27805014 | 0.79 | MAPT (0.51) | ALDH1A1MAPTLMNAMAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | claimed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | claimed |
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | disclosed |
| CN-102046609-A | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2011-05-04 | — | — | CN | disclosed |