Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805012 | 0.95 | ALDH1A1 (0.38) | MAPTLMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL27825618 | 0.92 | SLC6A2 (0.35) | MAPTLMNASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL27967259 | 0.85 | NCF1 (0.37) | HRH1KCNH2 | |
| SCHEMBL27967265 | 0.85 | MAPT (0.40) | MAPTLMNAKDM4EGAA | |
| SCHEMBL27825633 | 0.82 | CASP1 (0.44) | MAPTKDM4EKMT2A | |
| SCHEMBL27805094 | 0.81 | NCF1 (0.34) | MAPTGAASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27825621 | 0.79 | MAPT (0.35) | MAPTLMNAALDH1A1KDM4EHPGD | |
| SCHEMBL27804989 | 0.77 | SLC6A2 (0.36) | MAPTLMNASLC6A2SLC6A4HRH1 | |
| SCHEMBL27804977 | 0.77 | PIK3CA (0.48) | MAPTKDRSYKGBA1 | |
| SCHEMBL27805003 | 0.75 | MAPT (0.42) | MAPTLMNASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | claimed |
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | disclosed |