Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 4/20 | 0.33 |
| ▸ | CASP5 | P51878 | 4/20 | 0.33 |
| ▸ | CASP4 | P49662 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27805094 | 0.95 | NCF1 (0.34) | NCF1CASP1CASP5PIK3CAPIK3CB | |
| SCHEMBL27825618 | 0.95 | SLC6A2 (0.35) | NCF1HRH1KCNH2CASP1HTR1A | |
| SCHEMBL27967345 | 0.85 | MAPT (0.40) | HRH1KCNH2 | |
| SCHEMBL27967265 | 0.82 | MAPT (0.40) | DRD2CASP1CASP5CASP4PIK3CA | |
| SCHEMBL27805012 | 0.81 | ALDH1A1 (0.38) | HRH1KCNH2 | |
| SCHEMBL27825633 | 0.80 | CASP1 (0.44) | NCF1CASP1CASP5CASP4HTR1A | |
| SCHEMBL27825621 | 0.77 | MAPT (0.35) | DRD2KCNH2PIK3CAPIK3CB | |
| SCHEMBL27967258 | 0.76 | KMT2A (0.49) | NCF1CASP1CASP5CASP4PIK3CA | |
| SCHEMBL27825641 | 0.76 | SLC6A2 (0.35) | NCF1DRD3HRH1KCNH2CYP2D6 | |
| SCHEMBL27804977 | 0.74 | PIK3CA (0.48) | PIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | claimed |
| CN-102046609-B | pyrimidine derivative having cell-protective effect and use thereof | ZENYAKU KOGYO KK | 2014-05-14 | — | — | CN | disclosed |