Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.30 |
| ▸ | MTOR | P42345 | 2/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784328 | 0.89 | PIK3CA (0.38) | AKT1MTOR | |
| SCHEMBL27807946 | 0.86 | — | — | |
| SCHEMBL27786000 | 0.84 | MAPK10 (0.36) | AKT1MTOR | |
| SCHEMBL27807930 | 0.80 | MAPK10 (0.36) | AKT1MTOR | |
| SCHEMBL27808006 | 0.80 | PIK3CA (0.37) | MTOR | |
| SCHEMBL27785971 | 0.80 | GABRG2 (0.33) | KDM1A | |
| SCHEMBL28787383 | 0.80 | — | — | |
| SCHEMBL27786205 | 0.79 | GABRG2 (0.34) | — | |
| SCHEMBL27785925 | 0.79 | GABRA2 (0.36) | MTOR | |
| SCHEMBL2660434 | 0.79 | BMPR1A (0.38) | AKT1MTORRPS6KB1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |