Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12880578 | 0.94 | L3MBTL1 (0.43) | L3MBTL1TSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL23527410 | 0.78 | MEN1 (0.43) | L3MBTL1TSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL4645977 | 0.78 | L3MBTL1 (0.48) | L3MBTL1TSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL9782878 | 0.75 | MEN1 (0.44) | L3MBTL1ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9051490 | 0.75 | LMNA (0.49) | L3MBTL1ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29853736 | 0.74 | L3MBTL1 (0.45) | L3MBTL1TSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL4645643 | 0.74 | L3MBTL1 (0.45) | L3MBTL1TSHRALDH1A1HSD17B10MEN1 | |
| SCHEMBL2310457 | 0.72 | MEN1 (0.47) | L3MBTL1ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL151375 | 0.71 | TSHR (0.65) | TSHRALDH1A1KDM4EHPGDHTR2A | |
| SCHEMBL7912353 | 0.71 | ALDH1A1 (0.52) | TSHRALDH1A1HSD17B10HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102060793-B | Dual aryl tertiary amine azole compounds with biological activity as well as preparation method and medical application thereof | UNIV SOUTHWEST | 2013-03-20 | — | — | CN | disclosed |
| CN-102060793-A | Dual aryl tertiary amine azole compounds with biological activity as well as preparation method and medical application thereof | UNIV SOUTHWEST | 2011-05-18 | — | — | CN | disclosed |