Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SHMT1 | P34896 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27964610 | 0.88 | GRIN2D (0.38) | KDM4EALDH1A1FBP1LMNASHMT1 | |
| SCHEMBL27787923 | 0.84 | APEX1 (0.53) | KDM4EALDH1A1HPGDGAASMN1; SMN2 | |
| SCHEMBL27809827 | 0.84 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAFBP1GRIN2D | |
| SCHEMBL3031102 | 0.79 | RAB9A (0.53) | ALDH1A1GAASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27809770 | 0.79 | XDH (0.36) | SMN1; SMN2FBP1LMNAMAPTMEN1 | |
| SCHEMBL3725762 | 0.79 | XDH (0.44) | GAASMN1; SMN2FBP1MAPTMEN1 | |
| SCHEMBL27809792 | 0.71 | APEX1 (0.47) | KDM4EHPGDSMN1; SMN2FBP1MAPT | |
| SCHEMBL2768879 | 0.71 | FBP1 (0.64) | KDM4EALDH1A1HPGDGAAFBP1 | |
| SCHEMBL3032569 | 0.70 | FBP1 (0.37) | ALDH1A1HPGDGAASMN1; SMN2FBP1 | |
| SCHEMBL3032564 | 0.70 | FBP1 (0.37) | ALDH1A1HPGDGAASMN1; SMN2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801965-A | Indole compounds as inhibitors of cellular necrosis | LG LIFE SCIENCES LTD | 2010-08-11 | — | — | CN | disclosed |