Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 4/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824191 | 0.86 | ALOX5 (0.49) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL27803397 | 0.85 | ALOX5 (0.48) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL27817803 | 0.85 | KDM4E (0.54) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL27803545 | 0.81 | ALOX5 (0.52) | ALDH1A1LMNAMAPTMAPK1ALOX5 | |
| SCHEMBL27626587 | 0.80 | ALOX5 (0.71) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL27824237 | 0.79 | ALOX5 (0.51) | ALDH1A1MAPTKMT2AMEN1ALOX5 | |
| SCHEMBL27803421 | 0.79 | ALOX5 (0.51) | ALDH1A1KMT2AALOX5KDM4EPKM | |
| SCHEMBL28791714 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL1964753 | 0.76 | KDM4E (0.70) | ALDH1A1LMNAMAPTMAPK1KMT2A | |
| SCHEMBL14632042 | 0.75 | ALPL (0.40) | ALDH1A1LMNAMAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |