Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28026476 | 0.84 | LOXL2 (0.45) | LOXL2ESR1CES2CES1ALDH1A1 | |
| SCHEMBL3734266 | 0.82 | HSD17B3 (0.56) | HSD17B3ESR1ESR2KDM4EALDH1A1 | |
| SCHEMBL27798133 | 0.79 | HTR7 (0.56) | HSD17B3ESR1ESR2HDAC3HDAC1 | |
| SCHEMBL27798187 | 0.79 | HDAC3 (0.41) | HSD17B3ESR1ESR2HDAC3HDAC6 | |
| SCHEMBL27819249 | 0.77 | USP5 (0.40) | HSD17B3ESR1ESR2HTR7CES2 | |
| SCHEMBL28027049 | 0.74 | CES2 (0.36) | HSD17B3ESR1ESR2HDAC6CES2 | |
| SCHEMBL27623613 | 0.74 | HSD17B3 (0.65) | LOXL2HSD17B3HTR7 | |
| SCHEMBL7860414 | 0.72 | LMNA (0.51) | HDAC3HDAC6NCOR2HDAC1HDAC2 | |
| SCHEMBL27819250 | 0.71 | HDAC1 (0.47) | ESR1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27544691 | 0.70 | LOXL2 (0.42) | LOXL2F10HSD17B3HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104910051-A | Nitrone-substituted sulfonylarylamine derivative and preparation method thereof | UNIV ZHENGZHOU | 2015-09-16 | — | — | CN | disclosed |
| CN-101851176-B | Organic metal iridium catalyst with nitrone ligand | JIANGSU SINOCOMPOUND CATALYST CO LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-101851176-A | Novel nitrone ligand, organic metal iridium catalyst and preparation method and application thereof | SUZHOU SINOCOMPOUND TECHNOLOGY CO LTD | 2010-10-06 | — | — | CN | disclosed |