Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318224 | 0.82 | USP30 (0.56) | ALDH1A1 | |
| SCHEMBL1579576 | 0.81 | GAA (0.48) | DRD4DRD2DRD3MCHR1CHRNB2 | |
| SCHEMBL22720136 | 0.79 | RAB9A (0.58) | KDM4EALDH1A1HPGDRAB9AMEN1 | |
| SCHEMBL12435559 | 0.78 | RAB9A (0.60) | KDM4EALDH1A1HPGDRAB9AMEN1 | |
| SCHEMBL27677393 | 0.76 | CHEK1 (0.54) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27677400 | 0.76 | CHEK1 (0.54) | ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL27677399 | 0.74 | MAPT (0.47) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL28788213 | 0.73 | CHEK1 (0.47) | DRD4DRD2KDM4EALDH1A1MEN1 | |
| SCHEMBL1580074 | 0.73 | MAPK1 (0.56) | KDM4EALDH1A1HPGDRAB9AHSD17B10 | |
| SCHEMBL13161912 | 0.72 | HPGDS (0.56) | KDM4EALDH1A1HPGDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102170785-A | Benzimidazole derivatives and glycogen synthase kinase-3 beta inhibitors containing the same | ONCOTHERAPY SCIENCE INC | 2011-08-31 | — | — | CN | disclosed |