Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 13/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27915781 | 0.82 | ERN1 (0.47) | ERN1PIM1 | |
| SCHEMBL14222970 | 0.80 | ERN1 (0.45) | ERN1PIM1 | |
| SCHEMBL15309546 | 0.78 | ALDH1A1 (0.54) | ERN1PIM1THRBMAPT | |
| SCHEMBL6901379 | 0.76 | MEN1 (0.32) | ERN1THRBLMNAMAPT | |
| SCHEMBL18699231 | 0.75 | ERN1 (0.41) | ERN1PIM1LMNAMAPT | |
| SCHEMBL15002702 | 0.75 | ERN1 (0.45) | ERN1PIM1THRBLMNAMAPT | |
| SCHEMBL13176825 | 0.75 | ERN1 (0.45) | ERN1PIM1 | |
| SCHEMBL9218249 | 0.74 | LMNA (0.31) | THRBLMNA | |
| SCHEMBL95449 | 0.74 | THRB (0.50) | THRBLMNAMAPT | |
| SCHEMBL13258531 | 0.74 | ERN1 (0.44) | ERN1PIM1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101939313-B | 3,8-diaminotetrahydroquinoline derivative | ZERIA PHARM CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-101939313-A | 3,8-diamino tetrahydroquinoline derivative | ZERIA PHARM CO LTD | 2011-01-05 | — | — | CN | disclosed |