SCHEMBL9218249

SCHEMBL9218249

Nc1cc(N)c(C=O)c(C=O)c1

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3027694 0.85 TDP1 (0.33) MEN1KMT2ATDP1
SCHEMBL6901379 0.78 MEN1 (0.32) LMNAMEN1THRBBLMKMT2A
SCHEMBL27819554 0.74 ERN1 (0.46) LMNATHRB
SCHEMBL28068239 0.74 TDP1 (0.36) LMNAMEN1THRBBLMKMT2A
SCHEMBL135290 0.68 TDP1 (0.40) LMNAMEN1THRBBLMKMT2A
SCHEMBL2334691 0.68 CASP1 (0.42) LMNAMEN1THRBBLMKMT2A
SCHEMBL11804667 0.68 TDP1 (0.40) LMNAMEN1THRBBLMKMT2A
SCHEMBL8024070 0.68 TDP1 (0.40) LMNAMEN1THRBBLMKMT2A
SCHEMBL30442365 0.67 ERN1 (0.34) MEN1KMT2ATDP1
SCHEMBL725058 0.67 TDP1 (0.48) LMNAMEN1THRBBLMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0394846-B1 Organic photochromic compound SEIKISUI CHEMICAL CO LTD (JP) 1995-06-14 EP disclosed
EP-0394846-A2 Organic photochromic compound SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-10-31 EP disclosed