Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 12/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27802720 | 0.87 | NAMPT (0.47) | — | |
| SCHEMBL27823415 | 0.85 | AKR1C4 (0.41) | — | |
| SCHEMBL27823396 | 0.82 | ITK (0.44) | ITKTACR1 | |
| SCHEMBL27802749 | 0.80 | SCN5A (0.44) | ITKTACR1 | |
| SCHEMBL1495701 | 0.77 | PTGS2 (0.51) | ITK | |
| SCHEMBL22501639 | 0.71 | TRPV1 (0.52) | ITKP2RX7 | |
| SCHEMBL4881694 | 0.71 | DGAT2 (0.40) | ITKP2RX7NR1H2 | |
| SCHEMBL12757607 | 0.71 | NR1I2 (0.50) | ITK | |
| SCHEMBL12757537 | 0.70 | AKR1C3 (0.48) | ITK | |
| SCHEMBL4773435 | 0.70 | ALDH1A1 (0.48) | P2RX7NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101981003-B | Amide compounds, compositions and uses thereof | RENOVIS INC | 2014-07-02 | — | — | CN | disclosed |
| CN-101981003-A | Amide compounds, compositions and uses thereof | RENOVIS INC | 2011-02-23 | — | — | CN | disclosed |