Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18991593 | 0.85 | HSD17B10 (0.66) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5407957 | 0.75 | LMNA (0.63) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6234447 | 0.75 | ALOX15 (0.64) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28721775 | 0.74 | ALOX15 (0.43) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6954737 | 0.73 | ALOX15 (0.58) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8419574 | 0.72 | CYP1A2 (0.60) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1685055 | 0.72 | HSD17B10 (0.61) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL204727 | 0.71 | ALOX15 (0.64) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL707209 | 0.70 | ALOX15 (0.58) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11012986 | 0.70 | NPC1 (0.57) | HSD17B10NPC1SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101973942-A | Method for synthesizing 2-(1-benzimidazolyl) ethylamine | UNIV EAST CHINA NORMAL | 2011-02-16 | — | — | CN | claimed |
| CN-101973942-A | Method for synthesizing 2-(1-benzimidazolyl) ethylamine | UNIV EAST CHINA NORMAL | 2011-02-16 | — | — | CN | disclosed |