Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18991593 | 0.86 | HSD17B10 (0.66) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL6954737 | 0.84 | ALOX15 (0.58) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5407957 | 0.82 | LMNA (0.63) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1685055 | 0.80 | HSD17B10 (0.61) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL204727 | 0.79 | ALOX15 (0.64) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11845978 | 0.79 | ALOX15 (0.53) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL707209 | 0.78 | ALOX15 (0.58) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8419574 | 0.77 | CYP1A2 (0.60) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1735988 | 0.75 | ASAH1 (0.55) | HSD17B10KDM4ENPC1LMNASMN1; SMN2 | |
| SCHEMBL27823707 | 0.75 | ALOX15 (0.52) | ALOX15HSD17B10CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005005550-A1 | AZO COLORANT BASED ON 2-PHENYL-6-AMINO-7-METHOXYCARBONYL(3,4H)-CHINAZOLINE-4-ONE | CLARIANT GMBH (DE) | 2005-01-20 | — | — | WO | claimed |
| WO-2005005550-A1 | AZO COLORANT BASED ON 2-PHENYL-6-AMINO-7-METHOXYCARBONYL(3,4H)-CHINAZOLINE-4-ONE | CLARIANT GMBH (DE) | 2005-01-20 | — | — | WO | disclosed |