Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | JAK3 | P52333 | 5/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ITK | Q08881 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 6/20 | 0.37 |
| ▸ | CCND1 | P24385 | 3/20 | 0.37 |
| ▸ | CCND3 | P30281 | 3/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.36 |
| ▸ | CDK9 | P50750 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284506 | 0.91 | CAMK2D (0.43) | CAMK2DCSF1RTBK1CDK2JAK3 | |
| SCHEMBL27825349 | 0.81 | MAP3K5 (0.47) | JAK3EGFRCDK4CCND3CCNT1 | |
| SCHEMBL27844373 | 0.81 | SYK (0.45) | TBK1JAK3JAK2JAK1TYK2 | |
| SCHEMBL27825347 | 0.80 | CDK4 (0.46) | CAMK2DTBK1CDK2JAK3EGFR | |
| SCHEMBL28793684 | 0.80 | MAP3K5 (0.47) | JAK3EGFRCDK4CCND3CCNT1 | |
| SCHEMBL28793682 | 0.79 | CDK4 (0.46) | CAMK2DTBK1CDK2JAK3EGFR | |
| SCHEMBL27844447 | 0.78 | AURKA (0.47) | CAMK2DTBK1CDK2JAK3EGFR | |
| SCHEMBL27844363 | 0.76 | TBK1 (0.55) | CSF1RTBK1CDK2JAK3CCNA2 | |
| SCHEMBL1285307 | 0.76 | — | — | |
| SCHEMBL28793685 | 0.75 | AURKA (0.39) | CAMK2DCSF1RTBK1CDK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102341400-A | Pyrrolopyrimidines useful as kinase inhibitors | MEDICAL RES COUNCIL TECHNOLOGY | 2012-02-01 | — | — | CN | claimed |
| CN-102341400-A | Pyrrolopyrimidines useful as kinase inhibitors | MEDICAL RES COUNCIL TECHNOLOGY | 2012-02-01 | — | — | CN | disclosed |